Elena ISHOW

Molecular spectroscopy, photophysics, photochromism, polymers, nanomedicine, kinetics, organic physical chemistry

Photoactive and magnetic nanomaterials for data storage
Switchable nanomaterials for nanomedicine: toward multimodal bioimaging and on-command therapy

DIPLOMA

• Accredition to Direct Research (HDR) (ENS Cachan - May 2009)
• PhD  in chemistry and physical chemistry of transition metal complexes (University of Toulouse - Oct 1997)
• M.Sc. in chemistry and physical chemistry of transition metal complexes (University of Toulouse - June 2004)
• National certification of teaching physical sciences - major chemistry (agrégation de sciences physiques - option chimie - session 2003)

EDUCATION

• Assistant Professor at ENS Paris Saclay (ENS Cachan), France (1998-2010)
• sabbatical at MIT, Cambridge, USA (2003-2004) (group T. Swager)
• postdoc position at the Università di Bologna, Italie (1997-1998) (group V. Balzani)
• master and PhD in the Nanosciences group, CEMES, Toulouse (1994-1997) (group of J.-P. Launay and A. Gourdon)
• student at the Ecole Normale Supérieure de Cachan (class A"2 - 1990)

Research topics

• two-photon fluorescent nanoparticles for imaging in aqueous media
• surface photostructuration through bulk photoinduced migration for optical data storage
• thin-film emissive devices (organic lasers, electroluminescent diodes)
• hybrid magnetofluorescent nanoparticles for bioimaging and stimulated drug delivery in biological media

Supervision and committee

• 10 supervised and co-supervised PhD (7 defended)
• 7 post-doc researchers
• 41 research programs (22 as PI - ANR AAPG 2021,  PHC Tournesol 2019-20 et 2013-14, DGA 2018-22, RFI LUMOMAT 2015-18, Mechanobiology and Nano CNRS Challenge 2014-16 et 2018-19 , AAP Pluridisciplinarity of Nantes University  2014 & 2017, creation and coordinatuion of the Regional RFI LUMOMAT project  2011-13, AAP Regional Scientific Challenges 2011-14 ; Bresmat PdL-Bretagne 2011 ; C’Nano Ile-de-France 2009-10 ; ANR Young Researchers 2005-08 ; Marie Curie Outgoing Fellowship 2002)
• 5 HCERES assessement committees of laboratories
• 61 PhD defense committees

Major recent publications
(co-author of 85 publications and book articles, 2 patents)

1. Small 10.1002/smll.202403912, 2024 https://doi.org/10.1002/smll.202403912
E. Bequet, V. Silvestre, S. Cuenot, E. Ishow
Reversible light-triggered stretching of small-molecule photochromic organic nanoparticles.

2. Nanoscale 2022, 14, 5884-5898 https://doi.org/10.1039/C7NR06533G
T. Blondy, J. Boucard, C. Linot, E. Allard-Vannier, S. Nedellec, P. Hulin, J. Poly, E. Ishow, C. Blanquart
Impact of RAFT chain transfer agents on the polymeric shell density of magneto-fluorescent nanoparticles and their cellular uptake.

3. Adv. Opt. Mater. 2021, 9, 2100525  https://doi.org/10.1002/adom.202100525
F. Rodriguez, J. Jelken, N. Delpouve, A. Laurent, B. Garnier, J.-L. Duvail, F. Lagugné-Labarthet, E. Ishow
Exploiting light interferences to generate micrometer-high superstructures from monomeric azo materials with extensive orientational mobility.

4. J. Phys. Chem. C 2021, 125, 4665-4674 (supplementary cover) https://doi.org/10.1021/acs.jpcc.0c10287
T. Gallavardin, A. Mulas, L. Norel, S. Rigaut, A.Brosseau, R. Métivier, E. Ishow
Photoinduced architectural transformation of non-covalent fluorescent photochromic organic nanoparticles evidenced by amplified fluorescence photoswitching.

5. ChemPhysChem 2020, 23, 2502-2515 (front cover) https://doi.org/10.1002/cphc.202000633
S. Hoang, S. Olivier, S. Cuenot, A. Montillet, J. Bellettre, E. Ishow
Microfluidic assisted flash precipitation of photocrosslinkable fluorescent organic nanoparticles for fine size tuning and enhanced photoinduced processes.

6. ACS Appl. Mater. Interfaces 2019, 11, 32808-32814 https://pubs.acs.org/doi/abs/10.1021/acsami.9b12989
J. Boucard, T. Briolay, T. Blondy, M. Boujtita, S. Nedellec, P. Hulin, M. Grégoire, C. Blanquart, E. Ishow
Hybrid azo-fluorophore organic nanoparticles emissive turn-on probes for cellular endocytosis.